禁漫天堂

Jason Breves

Professor OF BIOLOGY

Address:
Department of Biology - CIS 110H
Skidmore College
Saratoga Springs, NY 12866

Telephone: (518) 580-5079
Fax: (518) 580-5071
E-mail: jbreves@skidmore.edu

Education:

• B.S., Roger Williams University (Marine Biology)
• M.S., University of Rhode Island (Oceanography)
• Ph.D., University of Hawaii (Molecular Biosciences and Bioengineering)
• Postdoctoral Studies, University of Massachusetts Amherst

Courses:

• Comparative Vertebrate Physiology (BI 244)
• Mammalian Physiology (BI 306)
• Endocrinology (BI 343)
• Aquatic Animal Physiology (BI 351)

Recent Support:

Recent Publications:

• Tao YT, Breves JP. 2024. Hypersalinity tolerance of mummichogs (Fundulus heteroclitus): A branchial transcriptomic analysis. Comparative Biochemistry and Physiology, Part D: 52: 101338.
• Breves JP, Posada MA, Tao YT, Shaughnessy CA. 2024. Salinity and prolactin regulate anoctamin 1 in the model teleost, Fundulus heteroclitus. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology: 327: R479-485.
• Breves JP, Shaughnessy CA. 2024. Endocrine control of gill ionocyte function in euryhaline fishes. Journal of Comparative Physiology B: 194: 663-684.
• Breves JP, Runiewicz ER, Richardson SG, Bradley SE, Hall DJ, McCormick SD. 2024. Transcriptional regulation of esophageal, intestinal, and branchial solute transporters by salinity, growth hormone, and cortisol in Atlantic salmon. Journal of Experimental Zoology A 341: 107-117.
• Celino-Brady FT, Breves JP, Seale AP. 2022. Sex-specific responses to growth hormone and luteinizing hormone in a model teleost, the Mozambique tilapia. General and Comparative Endocrinology 329: 114119.
• Breves JP, McKay IS, Koltenyuk V, Nelson NN, Lema SC, McCormick SD. 2022. Na⁺/HCO₃^- cotransporter 1 (nbce1) isoform gene expression during smoltification and seawater acclimation of Atlantic salmon. Journal of Comparative Physiology B 192: 577-592. 
• Seale AP, Breves JP. 2022. Endocrine and osmoregulatory responses to tidally-changing salinities in fishes. General and Comparative Endocrinology 326: 114071. 
• Breves JP, Puterbaugh KM, Bradley SE, Hageman AE, Verspyck AJ, Shaw LH, Danielson EC, Hou Y. 2022. Molecular targets of prolactin in mummichogs (Fundulus heteroclitus): ion transporters/channels, aquaporins, and claudins. General and Comparative Endocrinology 325: 114051. 
• Woo DW, Malintha GHT, Celino-Brady FT, Yamaguchi Y, Breves JP, Seale AP. 2022. Tilapia prolactin cells are thermosensitive osmoreceptors. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology 322: R609-R619. 
• Seale LA, Gilman CL, Zavacki AM, Larsen PR, Inokuchi M, Breves JP, Seale AP. 2021. Regulation of thyroid hormones and branchial iodothyronine deiodinases during freshwater acclimation in tilapia. Molecular and Cellular Endocrinology 538: 111450.
• Breves JP, Nelson, NN, Koltenyuk V, Petro-Sakuma CK, Celino-Brady FT, Seale AP. 2021. Enhanced expression of ncc1 and clc2c in the kidney and urinary bladder accompanies freshwater acclimation in Mozambique tilapia. Comparative Biochemistry and Physiology, Part A 260: 111021.
• Shaughnessy CA, Breves JP. 2021. Molecular mechanisms of Cl- transport in fishes: new insights and their evolutionary context. Journal of Experimental Zoology A 335: 207-216.
• Seale AP, Malintha T, Celino-Brady FT, Belcaid M, Yamaguchi Y, Lerner DT, Baltzegar DA, Borski RJ, Head T, Stoytcheva ZR, Breves JP. 2020. Transcriptional regulation of prolactin in a euryhaline teleost: characterization of gene promoters through in silico and transcriptomic analyses. Journal of Neuroendocrinology 32: e12905.  
• Breves JP, Popp EE, Rothenberg EF, Rosenstein CW, Maffett KM, Guertin RR. 2020. Osmoregulatory actions of prolactin in the gastrointestinal tract of fishes. General and Comparative Endocrinology 298: 113589.
• Breves JP, Springer-Miller RH, Chenoweth DA, Paskavitz AL, Chang AYH, Regish AM, Einarsdottir IE, Bj枚rnsson BT, McCormick SD. 2020. Cortisol regulates insulin-like growth-factor binding protein (igfbp) gene expression in Atlantic salmon parr. Molecular and Cellular Endocrinology 518: 110989.
• Petro-Sakuma CK, Celino-Brady FT, Breves JP, Seale AP. 2020. Growth hormone regulates intestinal gene expression of nutrient transporters in tilapia (Oreochromis mossambicus). General and Comparative Endocrinology 292: 113464.
• Breves JP, Starling JA, Popovski CM, Doud JM, Tipsmark CK. 2020. Salinity-dependent expression of ncc2 in opercular epithelium and gill of mummichog (Fundulus heteroclitus). Journal of Comparative Physiology B 190: 219-230.
• Breves JP. 2020. Hormonal control of aquaporins in fishes. In: Litwack G (Ed.), Vitamins & Hormones  (Vol. 112): Aquaporin Regulation. Academic Press. pp. 265-287.
  
  

Recent Abstracts/Presentations:

• Breves JP. Growth hormone and prolactin mediate critical life-history transitions in salmon. GroPro Meeting: Growth Hormone and Prolactin, Basic and Translational Science, August 2024, Stirling, Scotland.
• Breves JP, Posada MA, Tao YT, Shaughnessy CA. Anoctamin 1 supports seawater acclimation in Fundulus heteroclitus. 15th International Congress on the Biology of Fish, June 2024, Ann Arbor, MI.
• Richardson SG, Runiewicz ER, Bradley SE, Hall DJ, McCormick SD, Breves JP. Esophageal expression of Na+/H+ exchanger 2 and -3 (nhe2 and -3) gene transcripts in Atlantic salmon during smoltification and seawater acclimation. American Physiology Summit, April 2023, Long Beach, CA. 
• Runiewicz ER, Richardson SG, Bradley SE, Hall DJ, McCormick SD, Breves JP. Transcriptional regulation of gastrointestinal solute transporters by growth hormone and cortisol in Atlantic salmon. American Physiology Summit, April 2023, Long Beach, CA.
• Breves JP, Puterbaugh KM, Bradley SE, Hageman AE, Verspyck AJ, Shaw LH, Danielson EC, Hou Y. Molecular targets of prolactin signaling in euryhaline mummichogs (Fundulus heteroclitus). 14^th International Congress on the Biology of Fish, June 2022, Montpellier, France. 
• Seale AP, Woo DW, Malintha T, Celino-Brady FT, Yamaguchi Y, Breves JP. Effects of temperature on prolactin release from the tilapia pituitary. 14^th International Congress on the Biology of Fish, June 2022, Montpellier, France. 
• Breves JP. Invited: Prolactin and hydromineral balance in vertebrates: molecular and cellular insights from fishes. FASEB Science Research Conference: The Growth Hormone (GH)/Prolactin (PRL) Family in Biology and Disease, May 2022, Athens, OH.  
• Bradley SE, Puterbaugh KM, Hageman AE, Verspyck AJ, Shaw LH, Danielson EC, Hou Y, Breves JP. Prolactin directs branchial and intestinal gene expression of solute transporters and aquaporins in mummichog (Fundulus heteroclitus). Experimental Biology, April 2022, Philadelphia, PA.  
• Breves JP. Invited: Osmoregulatory plasticity in fishes: interplay between environmental conditions and systemic hormones. Experimental Biology, April 2022, Philadelphia, PA.  
• Celino-Brady FT, Breves JP, Seale AP.Sexually dimorphic responses to growth hormone and luteinizing hormone within the somatotropic and reproductive axes of tilapia. Experimental Biology, April 2022, Philadelphia, PA.  
• Breves JP. Invited: Salt and water balance in fishes: mechanisms of hormone action. Union College, Department of Biology, March 2022, Schenectady, NY.  
• Seale AP, Gilman CL, Zavacki AM, Larsen PR, Inokuchi M, Breves JP, Seale LA. The involvement of deiodinases and thyroid hormones during freshwater acclimation in a euryhaline fish. 12^th International Symposium on Selenium in Biology and Medicine, February 2022, Honolulu, HI.  
• Woo DW, Malintha T, Celino-Brady FT, Breves JP, Yamaguchi Y, Seale AP. Thermally induced changes in cell volume and hormone release in prolactin cells of Mozambique tilapia. 6^thMeeting of the North American Society for Comparative Endocrinology, May 2021. Virtual.
• Seale AP, Seale LA, Gilman CL, Zavacki AM, Larsen PR, Inokuchi M, Breves JP. Effects of freshwater acclimation on thyroid hormones and branchial deiodinase in Mozambique tilapia. 6^thMeeting of the North American Society for Comparative Endocrinology, May 2021. Virtual.
  
• Celino-Brady FT, Breves JP, Seale AP. Sex-dependent modulation of genes involved in growth and reproduction by growth hormone and luteinizing hormone in tilapia. 6^thMeeting of the North American Society for Comparative Endocrinology, May 2021. Virtual. 
• Breves JP. Invited: Endocrine perspectives on the growth of Atlantic salmon: effects of nutrition, stress, and endocrine disruptors. University of Hawaii SeaGrant, January 2020, Honolulu, HI. 

Selected Awards:

• Grace Evelyn Pickford Medal; International Federation of Comparative Endocrinological Societies (2025)
• New Investigator Award; American Physiological Society, Comparative and Evolutionary Physiology Section (2019)
• Gorbman-Bern New Independent Investigator Award; North American Society of Comparative Endocrinology (2019)
• Scholander Award; American Physiological Society, Comparative and Evolutionary Physiology Section (2013)
• Research Recognition Award; American Physiological Society, Comparative and Evolutionary Physiology Section (2013)
• Ruth L. Kirschstein National Research Service Awards (T32/F32), National Institutes of Health, NIMH & NIDDK (2011-2013)

Memberships:

• American Physiological Society (APS)
• North American Society for Comparative Endocrinology (NASCE)
• Society for Integrative and Comparative Biology (SICB)